Gene expression and cytopathic effect of vaccinia virus inactivated by psoralen and long-wave UV light

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Gene expression and cytopathic effect of vaccinia virus inactivated by psoralen and long-wave UV light.

Induction of the cytopathic effect (CPE) in cells infected with poxvirus seems ubiquitous in that it has been associated with all different strains and preparations of poxviruses, regardless of the replicating status of these viruses. The study of the mechanisms by which CPE is induced by nonreplicating poxviruses is hampered by the lack of any noncytopathic mutant strains and preparations. In ...

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Limited Effectiveness of Psoralen- and Ultraviolet-Inactivated Vaccinia Virus on SHIV Infection

The title and conclusions of the study recently published by Jones et al. (1) concluded that monkeys were protected from dying from a form of simian-human immunodeficiency virus (SHIV) by an psoralenand ultraviolet-inactivated vaccinia virus in a multi-envelope DNA-VV-protein (DVP). However, the findings in the study are more equivocal than indicated by the title because the effectiveness of th...

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Low-Dose, Long-Wave UV Light Does Not Affect Gene Expression of Human Mesenchymal Stem Cells

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Immunizing potential of vaccinia virus inactivated by ultraviolet rays

[1] In a precedent paper (1*), we have indicated that the vaccinia infection experiments of the rabbit skin can be inhibited by the intradermal injection of the equivalent virus inactivated by ultraviolet irradiation. [2] We have tried next, on one hand, to see if the complete virus is the sole inhibitory factor contained in the virulent materiel. [3] On the other hand, regarding to know if it ...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 1996

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.70.1.165-171.1996